Trial Design and Simulation
Trials Designs and Analysis Tools for a New Era of Drug Development
Advancements in genomics as well as disease pathway and drug discovery have advanced into clinical research. Master protocols have emerged in concert with seamless designs and an evolving regulatory landscape to facilitate accelerated approval, breakthrough therapy designation for refractory disorders, and tissue agonistic pathways for programs developing targeted therapeutics.
Telperian comprises leading experts in adaptive clinical trial design planning and simulation. We collaborate with clients to create statistical tools devised to optimize designs of future studies on the basis of existing evidence as well as forecast their resultant outcomes.
Resources
Master Protocols
Designs to simultaneously evaluating multiple drugs and/or disease populations in multiple substudies, allowing for efficient and accelerated drug development.
learn more
Seamless Trial Designs
Designs to consolidate the phases of drug development through rapid cohort expansion.
learn more
Biomarker Driven Studies
Statistical methods for establishing optimal treatment rules for matching patients to therapy.
learn more
Precision Analytics & Decision Sciences
Using Machine Learning to unlock external databased, characterize patient subtypes and design simple sequential trials.
learn more
Short Course: Drug development of non-cytotoxics
Half-day Shortcourse: Subtype Identification and Strategies for Trial Design.
learn more
